{"id":1957,"date":"2022-07-25T12:14:06","date_gmt":"2022-07-25T03:14:06","guid":{"rendered":"http:\/\/tarumi.co.jp\/blog\/?p=1957"},"modified":"2022-07-25T12:14:06","modified_gmt":"2022-07-25T03:14:06","slug":"post-1957","status":"publish","type":"post","link":"https:\/\/tarumi.co.jp\/blog\/?p=1957","title":{"rendered":"\u9ec4\u6591\u5909\u6027\u75c7\u6cbb\u7642\u306e\u65b0\u85ac \u30d0\u30d3\u30fc\u30b9\u30e2\u306b\u3064\u3044\u3066"},"content":{"rendered":"\n<p>2022\u5e747\u670823\u65e5\u306b\u3001\u300c\u30d0\u30d3\u30fc\u30b9\u30e2\u767a\u58f2\u8a18\u5ff5\u8b1b\u6f14\u4f1a in \u795e\u6238\u300d\u3092\u8074\u8b1b\u3057\u307e\u3057\u305f\u3002<br \/>\u8b1b\u5e2b\u306f\u795e\u6238\u5927\u5b66\u6960\u539f \u4ed9\u592a\u90ce\u5148\u751f\u3068\u4e09\u6728\u660e\u5b50\u5148\u751f\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">\u57fa\u790e<\/h4>\n\n\n\n<p>\u30fb\u5f93\u6765\u306e\u6297VEGF\u85ac\u306fVEGF(vascular endothelial growth factor\u3001\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u5897\u6b96\u56e0\u5b50)\u3068\u3044\u3046\u60aa\u7389\u56e0\u5b50\u306e\u307f\u304c\u5bfe\u8c61\u3060\u3063\u305f\u3002<br \/>\u30fb\u4e00\u65b9\u3001\u3053\u306e\u65b0\u85ac\u306fVEGF\u306b\u52a0\u3048\u3066Ang-2(Angiopoietin-2)\u3068\u3044\u3046\u60aa\u7389\u56e0\u5b50\u3082\u5bfe\u8c61\u3067\u3042\u308b\u3002\u300c\u6297VEGF\uff0b\u6297Ang-2\u300d=\u30d0\u30a4\u30b9\u30da\u30b7\u30d5\u30a3\u30c3\u30af\u6297\u4f53\u3068\u547c\u3076\u3002<br \/>\u30fbAng-2\u306f\u3001Ang-1\u306e\u30a2\u30f3\u30bf\u30b4\u30cb\u30b9\u30c8\u3067\u3042\u308b\u3002Ang-1\u306f\u5584\u7389\u56e0\u5b50\u3067\u3001Tie2\u30ec\u30bb\u30d7\u30bf\u30fc\u3092\u4ecb\u3057\u3066\u8840\u7ba1\u58c1\u7d30\u80de\u306e\u5b89\u5b9a\u6027\u3001\u5185\u76ae\u7d30\u80de\u9593\u306etight junction\u3068Blood Retinal Barrier\u6a5f\u80fd\u7dad\u6301\u306b\u5bc4\u4e0e\u3059\u308b\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/tarumi.co.jp\/blog\/wp-content\/uploads\/2022\/07\/AntiVEGF-vs-AntiAng-2-1024x563.png\" alt=\"\" class=\"wp-image-1962\" width=\"481\" height=\"263\"\/><figcaption><sub>\u6297VEGF\u6297\u4f53\u3001\u6297Ang-2\u6297\u4f53\u3001\u6297VEGF\u6297\u4f53+\u6297Ang-2\u6297\u4f53\u306e\u6bd4\u8f03<\/sub><\/figcaption><\/figure>\n\n\n\n<h4 class=\"wp-block-heading\">\u81e8\u5e8a<\/h4>\n\n\n\n<h5 class=\"wp-block-heading\">\u2460\u52b9\u679c<\/h5>\n\n\n\n<p>\u30fb\u30a2\u30a4\u30ea\u30fc\u30a2\u306b\u5bfe\u3057\u3066\u975e\u52a3\u52e2\u304c\u793a\u3055\u308c\u305f\u3002\u7d71\u8a08\u6709\u610f\u5dee\u306f\u306a\u3044\u3082\u306e\u306e\u3001\u30d0\u30d3\u30fc\u30b9\u30e2\u2267\u30a2\u30a4\u30ea\u30fc\u30a2\u3068\u3044\u3046\u5370\u8c61\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-1 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/tarumi.co.jp\/blog\/wp-content\/uploads\/2022\/07\/AMD_Thickness_Comparison2-1024x568.png\" alt=\"\" class=\"wp-image-1982\" width=\"307\" height=\"170\"\/><figcaption><sub>AMD\u3067\u306e\u7db2\u819c\u539a\u3055\u5909\u5316<\/sub><\/figcaption><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/tarumi.co.jp\/blog\/wp-content\/uploads\/2022\/07\/DME_Thickness_Comparison2-1024x524.png\" alt=\"\" class=\"wp-image-1983\" width=\"318\" height=\"162\"\/><figcaption><sub>DME\u3067\u306e\u7db2\u819c\u539a\u3055\u5909\u5316<\/sub><\/figcaption><\/figure>\n<\/div>\n<\/div>\n\n\n\n<h5 class=\"wp-block-heading\">\u2461\u6295\u4e0e\u9593\u9694<\/h5>\n\n\n\n<p>PRN(Pro ne Nata \u5fc5\u8981\u6642\u6295\u4e0e\u6cd5)\u3001TAE(Try and Extend \u8a08\u753b\u7684\u6295\u4e0e\u6cd5)\u3068\u3082\u3001\u30a2\u30a4\u30ea\u30fc\u30a2\u306f\u6700\u5927\u5ef6\u9577\uff13\u304b\u6708\u3060\u304c\u3001\u30d0\u30d3\u30fc\u30b9\u30e2\u306f\u6700\u5927\uff14\u304b\u6708\u307e\u3067\u5ef6\u9577\u53ef\u80fd\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">\u6297VEGF\u85ac\u306e\u6bd4\u8f03<\/h4>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><\/td><td>\u30a2\u30a4\u30ea\u30fc\u30a2<\/td><td>\u30eb\u30bb\u30f3\u30c6\u30a3\u30b9<\/td><td>\u30d9\u30aa\u30d3\u30e5<\/td><td>\u30d0\u30d3\u30fc\u30b9\u30e2<\/td><\/tr><tr><td>\u4e00\u822c\u540d<\/td><td>\u30a2\u30d5\u30ea\u30d9\u30eb\u30bb\u30d7\u30c8<\/td><td>\u30e9\u30cb\u30d3\u30ba\u30de\u30d6<\/td><td>\u30d6\u30ed\u30eb\u30b7\u30ba\u30de\u30d6<\/td><td>\u30d5\u30a1\u30ea\u30b7\u30de\u30d6<\/td><\/tr><tr><td>\u53d6\u6271\u3044<\/td><td>\u30d0\u30a4\u30a8\u30eb\u3001\u53c2\u5929\u88fd\u85ac<\/td><td>\u30ce\u30d0\u30eb\u30c6\u30a3\u30b9<\/td><td>\u30ce\u30d0\u30eb\u30c6\u30a3\u30b9<\/td><td>\u30ed\u30b7\u30e5\u3001\u4e2d\u5916\u88fd\u85ac<\/td><\/tr><tr><td>\u9069\u5fdc\u75be\u60a3<\/td><td>\u30fb\u4e2d\u5fc3\u7aa9\u4e0b\u8108\u7d61\u819c\u65b0\u751f\u8840\u7ba1\u3092\u4f34\u3046\u52a0\u9f62\u9ec4\u6591\u5909\u6027<br \/>\u30fb\u7db2\u819c\u9759\u8108\u9589\u585e\u75c7\u306b\u4f34\u3046\u9ec4\u6591\u6d6e\u816b<br \/>\u30fb\u75c5\u7684\u8fd1\u8996\u306b\u304a\u3051\u308b\u8108\u7d61\u819c\u65b0\u751f\u8840\u7ba1<br \/>\u30fb\u7cd6\u5c3f\u75c5\u9ec4\u6591\u6d6e\u816b<br \/>\u30fb\u8840\u7ba1\u65b0\u751f\u7dd1\u5185\u969c<\/td><td>\u30fb\u4e2d\u5fc3\u7aa9\u4e0b\u8108\u7d61\u819c\u65b0\u751f\u8840\u7ba1\u3092\u4f34\u3046\u52a0\u9f62\u9ec4\u6591\u5909\u6027\u75c7<br \/>\u30fb\u7db2\u819c\u9759\u8108\u9589\u585e\u75c7\u306b\u4f34\u3046\u9ec4\u6591\u6d6e\u816b<br \/>\u30fb\u75c5\u7684\u8fd1\u8996\u306b\u304a\u3051\u308b\u8108\u7d61\u819c\u65b0\u751f\u8840\u7ba1<br \/>\u30fb\u7cd6\u5c3f\u75c5\u9ec4\u6591\u6d6e\u816b<br \/>\u30fb\u672a\u719f\u5150\u7db2\u819c\u75c7<\/td><td>\u30fb\u4e2d\u5fc3\u7aa9\u4e0b\u8108\u7d61\u819c\u65b0\u751f\u8840\u7ba1\u3092\u4f34\u3046\u52a0\u9f62\u9ec4\u6591\u5909\u6027<br \/>\u30fb\u7cd6\u5c3f\u75c5\u9ec4\u6591\u6d6e\u816b<\/td><td>\u30fb\u4e2d\u5fc3\u7aa9\u4e0b\u8108\u7d61\u819c\u65b0\u751f\u8840\u7ba1\u3092\u4f34\u3046\u52a0\u9f62\u9ec4\u6591\u5909\u6027<br \/>\u30fb\u7cd6\u5c3f\u75c5\u9ec4\u6591\u6d6e\u816b<\/td><\/tr><tr><td>\u85ac\u4fa1<\/td><td>138,986\u5186<\/td><td>142,570\u5186<\/td><td>138,725\u5186<\/td><td>163,894\u5186<\/td><\/tr><\/tbody><\/table><figcaption><sub>\u6bd4\u8f03\u8868<\/sub><\/figcaption><\/figure>\n\n\n\n<p><span style=\"font-size:smaller\">\u203b\u4e0a\u8a18\u4ee5\u5916\u306b\u3001\u300c\u30e9\u30cb\u30d3\u30ba\u30de\u30d6 BS\u300d\u304c\u30eb\u30bb\u30f3\u30c6\u30a3\u30b9\u306e\u30d0\u30a4\u30aa\u30b7\u30df\u30e9\u30fc\u3068\u3057\u3066\u3001\u5343\u5bff\u304b\u3089\u85ac\u4fa179,348\u5186\u3067\u767a\u58f2\u3055\u308c\u3066\u3044\u308b\u3002\u9069\u5fdc\u75be\u60a3\u306f\u300c\u4e2d\u5fc3\u7aa9\u4e0b\u8108\u7d61\u819c\u65b0\u751f\u8840\u7ba1\u3092\u4f34\u3046\u52a0\u9f62\u9ec4\u6591\u5909\u6027\u3001\u75c5\u7684\u8fd1\u8996\u306b\u304a\u3051\u308b\u8108\u7d61\u819c\u65b0\u751f\u8840\u7ba1\u300d2023\/1\/13\u304b\u3089\u300c\u7cd6\u5c3f\u75c5\u9ec4\u6591\u6d6e\u816b\u300d\u3082\u9069\u5fdc\u75be\u60a3\u306b\u8ffd\u52a0\u3055\u305f\u30022023\/10\u304b\u3089\u300c\u7db2\u819c\u9759\u8108\u9589\u585e\u75c7\u306b\u4f34\u3046\u9ec4\u6591\u6d6e\u816b\u300d\u3082\u9069\u5fdc\u75be\u60a3\u306b\u8ffd\u52a0\u3055\u308c\u305f\u3002<\/span><\/p>\n\n\n\n<p>\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u8cea\u7591\u5fdc\u7b54\u304c\u3042\u3063\u305f\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u30fb\u5b9f\u969b\u306b\u4f7f\u3063\u305f\u624b\u5fdc\u3048\u3001\u5207\u308c\u5473\u306f\u3069\u3046\u304b\uff1f\u2192AMD\u306e\u672a\u6cbb\u7642\u306b\u3064\u3044\u3066\u306f\u30d0\u30d3\u30fc\u30b9\u30e2\u3067\u3088\u3044\u3002\u6cbb\u7642\u30b9\u30a4\u30c3\u30c1\u306b\u3064\u3044\u3066\u306f\u75c7\u4f8b\u4e0d\u8db3\u3067\u4e0d\u660e\u3002<br \/>\u30fb\u8996\u795e\u7d4c\u7e4a\u7dad\u306b\u5bfe\u3059\u308b\u5f71\u97ff\u306f\u3069\u3046\u304b\uff1f\u2192\u6297\uff36\uff25\uff27\uff26\u85ac\u306f\u8996\u795e\u7d4c\u7e4a\u7dad\u306b\u4e0d\u5229\u306b\u50cd\u304f\u304c\u3001\u30d0\u30d3\u30fc\u30b9\u30e2\u306f\u6297Ang-2\u306e\u50cd\u304d\u304c\u6709\u5229\u306b\u50cd\u304f\u3002<\/p><\/blockquote>\n\n\n\n<h4 class=\"wp-block-heading\">\u8b1b\u7fa9\u3092\u8074\u3044\u3066\u79c1\u306e\u611f\u60f3<\/h4>\n\n\n\n<p>\u30fb\u30d0\u30d3\u30fc\u30b9\u30e2\u306f\u30a2\u30a4\u30ea\u30fc\u30a2\u3088\u308a\u3082\u3001\u7db2\u819c\u6d6e\u816b\u306b\u5bfe\u3059\u308b\u52b9\u679c\u304c\u9ad8\u3044\u3088\u3046\u3060\u3002<br \/>\u30fb\u305f\u3060\u3001\u85ac\u4fa1\u306f\u9ad8\u3044 &amp; \u5b9f\u7e3e\u304c\u6d45\u3044\u3002\u3082\u3046\u5c11\u3057\u75c7\u4f8b\u84c4\u7a4d\u3092\u898b\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002<br \/><\/p>\n\n\n\n<hr class=\"wp-block-separator\"\/>\n\n\n\n<p>2022\/7\/31\u8ffd\u8a18\u3002\u4ee5\u4e0b\u306e\u85ac\u5264\u5e2b\u30b5\u30a4\u30c8\u304c\u3088\u304f\u307e\u3068\u307e\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><a href=\"https:\/\/passmed.co.jp\/di\/archives\/17364\">\u30d0\u30d3\u30fc\u30b9\u30e2\uff08\u30d5\u30a1\u30ea\u30b7\u30de\u30d6\uff09\u306e\u4f5c\u7528\u6a5f\u5e8f\uff1a\u985e\u85ac\u3068\u306e\u9055\u3044\u30fb\u6bd4\u8f03\u3010\u52a0\u9f62\u9ec4\u6591\u5909\u6027\u3011 &#8211; \u65b0\u85ac\u60c5\u5831\u30aa\u30f3\u30e9\u30a4\u30f3 (passmed.co.jp)<\/a><\/p>\n\n\n\n<p>2022\/1\/23\u8ffd\u8a18<\/p>\n\n\n\n<p>\u795e\u6238\u5927\u5b66\u773c\u79d1\u4e09\u6728\u660e\u5b50\u5148\u751f\u306b\u3088\u308b\u3068\u3001<\/p>\n\n\n\n<p>\u65b0\u751f\u8840\u7ba1\u9ec4\u6591\u75c7\u3067\u306e\u6cbb\u7642\u30b9\u30a4\u30c3\u30c1\u306f<br \/>\u30fb\u3059\u3050\u52b9\u304f\u3053\u3068\u3082\u3042\u308b\u304c\u30011,2\u304b\u6708\u305f\u3063\u3066\u304b\u3089\u52b9\u3044\u3066\u304f\u308b\u5834\u5408\u304c\u3042\u308b\u3002\u7db2\u819c\u4e0b\u9ad8\u53cd\u5c04\u75c5\u5de3 (subretinal hyper-reflective material: SHRM)\u304c\u51fa\u306a\u3044\u9650\u308a\u7d9a\u3051\u308b\u3002<br \/>\u30fb\u7d30\u52d5\u8108\u7624\u304c\u3042\u308b\u5834\u5408\u306b\u306f\u3088\u304f\u52b9\u304f\u3002<br \/>\u3000\u2191<br \/>SHRM\u306f\u3001\u6ef2\u51fa\u578b\u52a0\u9f62\u9ec4\u6591\u5909\u6027\u60a3\u8005\u306e\u8996\u529b\u53ca\u3073\u7dda\u7dad\u5316\u7d44\u7e54\u3068\u76f8\u95a2\u3057\u3001\u6297VEGF\u85ac\u306e\u6cbb\u7642\u52b9\u679c\u4e88\u6e2c\u306b\u6709\u7528\u3067\u3042\u308b\u3068\u3055\u308c\u308b\u3002cf.  Kawashima, Y., Hata, M., Oishi, A., Ooto, S., Yamashiro, K., Tamura, H., Miyata, M.,Uji, A., Ueda-Arakawa, N., and Tsujikawa, A. (2017) Association of Vascular VersusAvascular Subretinal Hyperreflective Material With Aflibercept Response in Age-related Macular Degeneration. American journal of ophthalmology 181, 61-70<\/p>\n","protected":false},"excerpt":{"rendered":"<p>2022\u5e747\u670823\u65e5\u306b\u3001\u300c\u30d0\u30d3\u30fc\u30b9\u30e2\u767a\u58f2\u8a18\u5ff5\u8b1b\u6f14\u4f1a in \u795e\u6238\u300d\u3092\u8074\u8b1b\u3057\u307e\u3057\u305f\u3002\u8b1b\u5e2b\u306f\u795e\u6238\u5927\u5b66\u6960\u539f \u4ed9\u592a\u90ce\u5148\u751f\u3068\u4e09\u6728\u660e\u5b50\u5148\u751f\u3067\u3057\u305f\u3002 \u57fa\u790e \u30fb\u5f93\u6765\u306e\u6297VEGF\u85ac\u306fVEGF(vascular endothelial gro <a class=\"read-more\" href=\"https:\/\/tarumi.co.jp\/blog\/?p=1957\">READ MORE<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-1957","post","type-post","status-publish","format-standard","hentry","category-20"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/tarumi.co.jp\/blog\/index.php?rest_route=\/wp\/v2\/posts\/1957"}],"collection":[{"href":"https:\/\/tarumi.co.jp\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tarumi.co.jp\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tarumi.co.jp\/blog\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/tarumi.co.jp\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1957"}],"version-history":[{"count":0,"href":"https:\/\/tarumi.co.jp\/blog\/index.php?rest_route=\/wp\/v2\/posts\/1957\/revisions"}],"wp:attachment":[{"href":"https:\/\/tarumi.co.jp\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1957"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tarumi.co.jp\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1957"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tarumi.co.jp\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1957"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}